EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 22-Jun-2026 13:15 ET (22-Jun-2026 17:15 GMT/UTC)

Creatine may supercharge immune cells that are key to fighting cancer

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

The UCLA study, conducted in mouse models and human cells and published in iScience, shows dendritic cells — the immune cells that direct killer T cells to attack cancer — ramp up their intake of creatine inside tumors and depend on it to function effectively in this nutrient-poor environment.

Using patient-derived research models to study deadly DNA loops

Sanford Burnham Prebys
Peer-Reviewed Publication

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from a glacier. Scientists at Sanford Burnham Prebys Medical Discovery Institute and their colleagues published findings May 28, 2026, in Genome Medicine demonstrating significant similarities between samples of tumors featuring these stranded DNA fragments and research models developed using these tumor samples. This close match provides scientists with greater confidence in using these models to learn how to better diagnose and treat cancers with these splintered spots of DNA.

Journal: Genome Medicine

Some regions of the human genome considered junk DNA could play a key role in cancer

University of Barcelona
Peer-Reviewed Publication

Many repetitive regions of the genome have been considered “junk DNA” because the technologies available did not allow them to be studied at sufficient resolution. This is the case with the SST1/NBL2 macrosatellites, considered irrelevant and, until now, virtually invisible, which could have a more complex and decisive biological role than previously thought in nuclear organization, genome regulation, chromosomal instability and even cancer.

Journal: Trends in Genetics

TIGIT: A promising target for overcoming tumor immunotherapy resistance

Chinese Medical Journals Publishing House Co., Ltd.
Peer-Reviewed Publication

A new review in the Journal of Pancreatology explores TIGIT as a pivotal immune checkpoint for cancer immunotherapy. It details TIGIT’s immunosuppressive mechanisms, its correlation with poor prognosis, and the superior efficacy of anti-TIGIT/PD-1 combination therapy in overcoming resistance to conventional immune checkpoint inhibitors.

Journal: Journal of Pancreatology
Funder: Shandong Provincial Natural Science Foundation, China

Study in flies reveals how some tumours eliminate healthy neighbouring cells to grow

Institute for Research in Biomedicine (IRB Barcelona)
Peer-Reviewed Publication

The study, led by IRB Barcelona, shows that tumours with chromosomal instability can promote their own growth by damaging the surrounding healthy tissues.

Senescent tumour cells release signals that block the proliferation of neighbouring cells, ultimately inducing their death.

Published in EMBO Reports, the study identifies a new interaction mechanism between the tumour and its environment, which could open new avenues for researching targeted therapies against senescent cells.

Journal: EMBO Reports

UT MD Anderson shares latest research breakthroughs

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

AI-powered atlas uncovered tertiary lymphoid structures as prognostic biomarkers

Research reveals drivers of treatment resistance in KRAS-mutant colorectal cancer and insights on which patients may benefit most from immunotherapy for various cancers

Scientists uncover the molecular pathways involved in blood vessel plaques

Immunotherapy could help treat potentially fatal fungal pneumonias

Direct-to-consumer pharmacies may lower costs for generic prescriptions

Treatment delays in early age–onset colorectal cancer

JAMA Network
Peer-Reviewed Publication

About The Study: In this cross-sectional study, early age–onset colorectal cancer (EOCRC) was associated with improved overall survival compared with average age–onset colorectal cancer; however, treatment delays were independently associated with worse survival among patients with EOCRC. Language barriers could be a potentially modifiable risk factor associated with delayed treatment and may provide an opportunity to improve timely care and outcomes in EOCRC.

Journal: JAMA Oncology

A blood signature for lung cancer risk: 14 proteins identify people who could benefit from cancer prevention drugs

The Francis Crick Institute
Peer-Reviewed Publication

Researchers at the Francis Crick Institute and University College London (UCL), funded by Cancer Research UK and the European Research Council (ERC), have identified a 14-protein signature in the blood that can predict lung cancer risk more than five years before diagnosis.

Journal: Cell

A single starting point for different cancers

University of Liège
Peer-Reviewed Publication

How do different cancer subtypes arise? Do they originate from distinct cells, or from a single multipotent cell capable of differentiating into multiple cell types? This question, debated for decades in cancer biology, is now gaining new insight thanks to the work of the Laboratory of Experimental Pathology (ULiège), in collaboration with researchers from Université Paris Cité and Sorbonne University.

Journal: Cell Reports

Rare eyelid tumor highlights the importance of accurate diagnosis and pathological evaluation

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — June 4, 2026 — A new case report was published in Volume 13 of Oncoscience on April 2, 2026, titled “Sebaceous adenoma of the eyelid: A clinical, histopathological, and immunohistochemical perspective.”

Journal: Oncoscience

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