EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 23-Jun-2026 01:16 ET (23-Jun-2026 05:16 GMT/UTC)

Which genes contribute to early-onset breast cancer in Black women?

Wiley
Peer-Reviewed Publication

Black women experience disproportionately elevated risks of developing and dying from early-onset breast cancer. New research published by Wiley online in CANCER reveals the genes that are most likely to be mutated to contribute to these increased risks.

Journal: Cancer

Weight loss treatments linked to lower risk of obesity-related cancers in people without diabetes

European Society for Medical Oncology
Peer-Reviewed Publication

A study of more than 229,000 obese adults without diabetes in the United States has shown that weight loss drugs are associated with a decreased risk of obesity-related cancers. The research, published in Annals of Oncology, found that GLP-1 receptor agonists (GLP-1 RAs), such as semaglutide and tirzepatide, were associated with a 41% decrease in the overall risk of developing cancer among non-diabetic patients who used the drugs for weight management, compared to those who relied on diet and exercise alone.

Journal: Annals of Oncology

Mayo Clinic study shows AI can reveal brain tumor risks without costly genetic testing

Mayo Clinic
Peer-Reviewed Publication

Mayo Clinic researchers and collaborators have shown that artificial intelligence (AI) can analyze routine pathology slides to help classify meningiomas, the most common primary brain tumor in adults, and predict a patient's risk of tumor recurrence.

Journal: The Lancet Digital Health

Study proposes reconsidering how histone deacetylase inhibitors work in cancer treatment

Baylor College of Medicine
Peer-Reviewed Publication

Researchers are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function. For decades, scientists believed that these drugs blocked HDAC enzymes, which drive cancer development by altering how genes are turned on and off. The current study suggests that HDAC inhibitors do not necessarily rely solely on HDAC inhibition but also may affect other pathways.

Journal: Signal Transduction and Targeted Therapy

Creatine may supercharge immune cells that are key to fighting cancer

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

The UCLA study, conducted in mouse models and human cells and published in iScience, shows dendritic cells — the immune cells that direct killer T cells to attack cancer — ramp up their intake of creatine inside tumors and depend on it to function effectively in this nutrient-poor environment.

Using patient-derived research models to study deadly DNA loops

Sanford Burnham Prebys
Peer-Reviewed Publication

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from a glacier. Scientists at Sanford Burnham Prebys Medical Discovery Institute and their colleagues published findings May 28, 2026, in Genome Medicine demonstrating significant similarities between samples of tumors featuring these stranded DNA fragments and research models developed using these tumor samples. This close match provides scientists with greater confidence in using these models to learn how to better diagnose and treat cancers with these splintered spots of DNA.

Journal: Genome Medicine

Some regions of the human genome considered junk DNA could play a key role in cancer

University of Barcelona
Peer-Reviewed Publication

Many repetitive regions of the genome have been considered “junk DNA” because the technologies available did not allow them to be studied at sufficient resolution. This is the case with the SST1/NBL2 macrosatellites, considered irrelevant and, until now, virtually invisible, which could have a more complex and decisive biological role than previously thought in nuclear organization, genome regulation, chromosomal instability and even cancer.

Journal: Trends in Genetics

TIGIT: A promising target for overcoming tumor immunotherapy resistance

Chinese Medical Journals Publishing House Co., Ltd.
Peer-Reviewed Publication

A new review in the Journal of Pancreatology explores TIGIT as a pivotal immune checkpoint for cancer immunotherapy. It details TIGIT’s immunosuppressive mechanisms, its correlation with poor prognosis, and the superior efficacy of anti-TIGIT/PD-1 combination therapy in overcoming resistance to conventional immune checkpoint inhibitors.

Journal: Journal of Pancreatology
Funder: Shandong Provincial Natural Science Foundation, China

Study in flies reveals how some tumours eliminate healthy neighbouring cells to grow

Institute for Research in Biomedicine (IRB Barcelona)
Peer-Reviewed Publication

The study, led by IRB Barcelona, shows that tumours with chromosomal instability can promote their own growth by damaging the surrounding healthy tissues.

Senescent tumour cells release signals that block the proliferation of neighbouring cells, ultimately inducing their death.

Published in EMBO Reports, the study identifies a new interaction mechanism between the tumour and its environment, which could open new avenues for researching targeted therapies against senescent cells.

Journal: EMBO Reports

UT MD Anderson shares latest research breakthroughs

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

AI-powered atlas uncovered tertiary lymphoid structures as prognostic biomarkers

Research reveals drivers of treatment resistance in KRAS-mutant colorectal cancer and insights on which patients may benefit most from immunotherapy for various cancers

Scientists uncover the molecular pathways involved in blood vessel plaques

Immunotherapy could help treat potentially fatal fungal pneumonias

Direct-to-consumer pharmacies may lower costs for generic prescriptions

15
16
17
18
19