New step toward programmable chemistry may help reduce drug side effects
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Jun-2026 18:15 ET (21-Jun-2026 22:15 GMT/UTC)
Drug delivery and diagnostic imaging often lack specificity, but a new “TRACE” method lets specially‑caged compounds stay inert until a target cell’s enzymes quickly remove the cage, potentially allowing for more precise drug delivery and sharper diagnostic imaging.
A new study in Science Bulletin presents DVSTP, a deep learning system that integrates pathology images with spatial transcriptomics and proteomics to map intra-tumor heterogeneity. DVSTP predicts molecular profiles from routine pathology slides, making spatial multi-omics more accessible. Whole–tumor 3D reconstruction reveals that SRSF6 drives immune exclusion and is associated with poor clinical outcomes.
Women with abnormal mammograms often have to wait for weeks to find out whether they have breast cancer.
Now, researchers at UC San Francisco and UC Berkeley have found a way to help reduce the wait and the worry by using AI to quickly identify those who are most likely to have the disease. By triaging these patients, the AI-guided workflow takes women with abnormal scans through the diagnostic process — from imaging to evaluation and sometimes even biopsy — in a single day.