Damage to brain’s white matter may play key role in neurodegenerative disease, and could be target for future treatments
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This month, we’re spotlighting Parkinson’s disease research in recognition of Parkinson’s Awareness Month. Here, we’ll share the latest research on Parkinson’s disease, how scientists are working to better understand its causes and progression, advances in treatment and care, and more.
Updates every hour. Last Updated: 24-Apr-2026 10:17 ET (24-Apr-2026 14:17 GMT/UTC)
In a new study published in Nature, Cambridge researchers have discovered that damage to white matter can trigger features associated with neurodegenerative disease. Unexpectedly, these are not harmful, but instead are essential components of brain regeneration.
Up to one in three people with Parkinson’s disease use at least one psychotropic medication, a recent study from the University of Eastern Finland shows. People with Parkinson’s disease were using psychotropics more frequently than controls already before the diagnosis, and psychotropic use increased as the disease progressed.
Van Andel Institute has named internationally recognized scientist Glenda Halliday, Ph.D., as the recipient of its 2026 Jay Van Andel Award for Outstanding Achievement in Parkinson’s Disease Research. The award will be presented during Grand Challenges in Parkinson’s Disease, VAI’s flagship annual Parkinson’s disease symposium, Sept. 23–24.
Analysis of microbes in the gut can reveal whether a person faces an elevated risk of Parkinson’s disease, before they have developed any symptoms, suggests a new study led by University College London (UCL) researchers.
NTU Singapore scientists have identified a fat-producing enzyme (GPAT) in brain cells that amplifies the damage caused by α-synuclein, the protein linked to Parkinson's disease. GPAT delivers a "double hit" — impairing cells' energy-producing machinery while increasing the protein's toxicity. Reducing GPAT activity led to less brain cell damage in lab models. The findings point to a potential new treatment target for a disease that currently has no cure.