Ferrocene conjugated glutathione consumption for enhanced ferroptosis therapy and chemotherapy
Peer-Reviewed Publication
This month, we’re focusing on artificial intelligence (AI), a topic that continues to capture attention everywhere. Here, you’ll find the latest research news, insights, and discoveries shaping how AI is being developed and used across the world.
Updates every hour. Last Updated: 17-Nov-2025 15:11 ET (17-Nov-2025 20:11 GMT/UTC)
Research has shown that ferroptosis can overcome chemotherapy resistance induced by apoptosis, making the combination of chemotherapy and ferroptosis a very promising strategy for cancer treatment. However, the high levels of glutathione in the tumor environment and insufficient intracellular iron content limit the anticancer effects mediated by ferroptosis. Recently, a study published in Nano Research utilized the tumor environment to achieve a "multi-machine integrated" combined strategy, enhancing the therapeutic effects of chemotherapy and ferroptosis. The study was published in Nano Research with the DOI of 10.26599/NR.2025.94907298.
Carnegie Mellon University Africa announced today that the African Engineering and Technology Network (Afretec) has signed its ninth university partner, Universidade Agostinho Neto. The network, launched in 2022, provides a vehicle for technology-focused universities in Africa to engage in deep collaboration to drive digital growth, create technology development and job growth, and shape policy change.
A leading large language model displays behaviors that resemble a hallmark of human psychology: cognitive dissonance. In a report published this month in PNAS (Proceedings of the National Academy of Sciences), researchers found that OpenAI’s GPT-4o appears driven to maintain consistency between its own attitudes and behaviors, much like humans do.
In a paper published in SCIENCE CHINA Earth Sciences, an international team of researchers present the new details about the enhancement of aragonite precipitation during photosynthesis in Skeletonema costatum in artificial and natural seawater. By directly measuring cell surfaces, it reveals the mechanism of diatom-mediated promotion of CaCO3 precipitation. Based on this mechanism, it suggests that diatom-mediated calcification can occur in the oceans, which is supported by relevant phenomena. The newly found calcification pathway connects particulate inorganic and organic carbon flux, facilitating the reassessment of marine carbon export fluxes and CO2 sequestration efficiency. And this discovery may have significant implications for evaluating marine carbon cycling and predicting the impacts of future ocean acidification.