Early signs of Parkinson’s can be identified in the blood
Peer-Reviewed Publication
This month, we’re spotlighting Parkinson’s disease research in recognition of Parkinson’s Awareness Month. Here, we’ll share the latest research on Parkinson’s disease, how scientists are working to better understand its causes and progression, advances in treatment and care, and more.
Updates every hour. Last Updated: 23-Apr-2026 09:16 ET (23-Apr-2026 13:16 GMT/UTC)
A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson’s disease in its earliest stages, before extensive brain damage has occurred. The biological processes leave measurable traces in the blood, but only for a limited period. The discovery thus reveals a window of opportunity that could be crucial for future treatment, but also for early diagnosis via blood tests, which could begin to be tested in healthcare within five years.
New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK Dementia Research Institute at UCL (University College London).
Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Amyotrophic Lateral Sclerosis are marked by the buildup of misfolded proteins that slowly destroy brain cells, yet treatments that address this root cause are still lacking. Interestingly, researchers provide a comprehensive review of the role of heat shock protein 70 (Hsp70) molecular chaperones in several neurodegenerative diseases. Notably, Hsp70 exert neuroprotective effects and mitigate the occurrence of pathological protein aggregates.
Parkinson’s disease is more common among individuals with a higher socioeconomic status and in the northern provinces of the Netherlands. In the southern provinces, Parkinson’s occurs less frequently. Men are at greater risk than women, and the risk increases with age, peaking between 75 and 85 years. These findings come from a large-scale study by researchers at Utrecht University and Radboudumc on the number of new patients and the distribution of Parkinson’s disease in the Netherlands between 2017 and 2022.