Meetings

Previously, the primary endpoint results of the NRG-LU005 study assessing the addition of the immunotherapy drug atezolizumab to standard of care concurrent chemoradiation for limited-state small cell lung cancer was reported at the American Society for Radiation Oncology 2024 Annual Meeting. Those results showed that adding atezolizumab did not improve overall survival (OS) for this patient population. At the same time, an exploratory analysis reported longer median OS among patients who received twice-a-day radiation, though RT schedule was not randomized. As a follow up to that study, a patient-reported outcomes (PRO) analysis explored the impact of the NRG-LU005 treatment regimens on quality of life (QOL). The results of this PRO analysis were recently reported as a late-breaking abstract at the ASTRO 2025 Annual Meeting in San Francisco, California.

Previously, results from the photon cohort of the NRG-BN001, a signal seeking Phase II randomized trial, indicated that photon radiation dose intensification (75 Gy) did not demonstrate improvement in overall survival (OS) for patients with newly diagnosed glioblastoma (GBM). The recent analysis of the proton cohort revealed improved survival for patients receiving proton therapy at 75 Gy. Because this data met the pre-defined survival improvement threshold, they could be used to design and conduct a definitive phase III randomized trial.

Results from the health-related quality of life (HRQOL) analysis of the University of Pennsylvania and RTOG Foundation RadComp study indicated that both photon and proton radiation treatment options yielded similar, excellent HRQOL outcomes for women with non-metastatic breast cancer. RadComp was the first randomized study comparing proton to photon radiation for breast cancer treatment.

Results of the NRG Oncology NRG-GU005 clinical study comparing stereotactic body radiation therapy (SBRT) to moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) for patients with localized immediate risk prostate cancer indicate that the use of SBRT improved bowel health related quality of life (HRQOL) in this patient population. There was no significant improvement seen for the other primary objectives including urinary HRQOL and there was a lack of improvement in distant-free survival for patients.

The Associated Professional Sleep Societies is accepting research abstracts and session proposal submissions for SLEEP 2026, the 40^th annual meeting of the APSS, which will be held June 14 to 17 at the Baltimore Convention Center.

University of Cincinnati Cancer Center researchers will present abstracts at the American Society for Radiation Oncology (ASTRO) annual meeting Sept. 27 through Oct. 1 in San Francisco.

The University of Cincinnati Cancer Center’s Ahmet Kaynak examined the unique tumor microenvironment of pancreatic ductal adenocarcinoma cells, identified one of the key proteins that aids tumor treatment resistance and developed a new drug targeting this protein that reduced tumor size and increased survival in animal models.

Hundreds of physicists from around the world will convene to present new research at the 2025 Fall Meeting of the American Physical Society’s Division of Nuclear Physics. The conference will be held in person only at the Hilton Chicago in Chicago Oct. 17-20.