News from China
Updates every hour. Last Updated: 19-Jan-2026 07:11 ET (19-Jan-2026 12:11 GMT/UTC)
Saturated alcohols electrocatalytic oxidations on Ni‑Co bimetal oxide featuring balanced B‑and L‑acidic active sites
Shanghai Jiao Tong University Journal CenterPeer-Reviewed Publication
Investigating structural and hydroxyl group effects in electrooxidation of alcohols to value-added products by solid-acid electrocatalysts is essential for upgrading biomass alcohols. Herein, we report efficient electrocatalytic oxidations of saturated alcohols (C1-C6) to selectively form formate using NiCo hydroxide (NiCo–OH) derived NiCo2O4 solid-acid electrocatalysts with balanced Lewis acid (LASs) and Brønsted acid sites (BASs). Thermal treatment transforms BASs-rich (89.6%) NiCo–OH into NiCo2O4 with nearly equal distribution of LASs (53.1%) and BASs (46.9%) which synergistically promote adsorption and activation of OH− and alcohol molecules for enhanced oxidation activity. In contrast, BASs-enriched NiCo–OH facilitates formation of higher valence metal sites, beneficial for water oxidation. The combined experimental studies and theoretical calculation imply the oxidation ability of C1-C6 alcohols increases as increased number of hydroxyl groups and decreased HOMO–LUMO gaps: methanol (C1) < ethylene glycol (C2) < glycerol (C3) < meso-erythritol (C4) < xylitol (C5) < sorbitol (C6), while the formate selectivity shows the opposite trend from 100 to 80%. This study unveils synergistic roles of LASs and BASs, as well as hydroxyl group effect in electro-upgrading of alcohols using solid-acid electrocatalysts.
- Journal
- Nano-Micro Letters
RNA modification m⁶A emerges as key player in cancer development and therapy
Sichuan International Medical Exchange and Promotion AssociationPeer-Reviewed Publication
In a review published in Molecular Biomedicine, a team of Chinese scientists summarizes the pivotal role of N⁶-methyladenosine (m⁶A)—the most abundant chemical modification in eukaryotic mRNA—in cancer biology. The authors describe how m⁶A regulators (writers, erasers, and readers) influence tumor progression, metastasis, treatment resistance, and the tumor microenvironment. They also discuss emerging therapeutic strategies, including small-molecule inhibitors, RNA-based editing technologies, and combination therapies, highlighting m⁶A's potential as a diagnostic and prognostic biomarker and a target for precision oncology.
- Journal
- Molecular Biomedicine
Chirality‑induced suppression of singlet oxygen in lithium–oxygen batteries with extended cycle life
Shanghai Jiao Tong University Journal CenterPeer-Reviewed Publication
Lithium–oxygen (Li–O2) batteries are perceived as a promising breakthrough in sustainable electrochemical energy storage, utilizing ambient air as an energy source, eliminating the need for costly cathode materials, and offering the highest theoretical energy density (~ 3.5 kWh kg–1) among discussed candidates. Contributing to the poor cycle life of currently reported Li–O2 cells is singlet oxygen (1O2) formation, inducing parasitic reactions, degrading key components, and severely deteriorating cell performance. Here, we harness the chirality-induced spin selectivity effect of chiral cobalt oxide nanosheets (Co3O4 NSs) as cathode materials to suppress 1O2 in Li–O2 batteries for the first time. Operando photoluminescence spectroscopy reveals a 3.7-fold and 3.23-fold reduction in 1O2 during discharge and charge, respectively, compared to conventional carbon paper-based cells, consistent with differential electrochemical mass spectrometry results, which indicate a near-theoretical charge-to-O2 ratio (2.04 e−/O2). Density functional theory calculations demonstrate that chirality induces a peak shift near the Fermi level, enhancing Co 3d–O 2p hybridization, stabilizing reaction intermediates, and lowering activation barriers for Li2O2 formation and decomposition. These findings establish a new strategy for improving the stability and energy efficiency of sustainable Li–O2 batteries, abridging the current gap to commercialization.
- Journal
- Nano-Micro Letters
An effective encoding of human medical conditions in disease space provides a versatile framework for deciphering disease associations
Higher Education Press- Journal
- Quantitative Biology
iPSC modification strategies to induce immune tolerance
Higher Education PressDr. Kai Wang and his team published a review in Life Medicine to summarize the iPSC modification strategies to reach immune escape and reduce graft versus host disease (GvHD).
- Journal
- Life Medicine
Floating hydrovoltaic device harvests energy from raindrops
Science China PressPeer-Reviewed Publication
Researchers at Nanjing University of Aeronautics and Astronautics have developed a water-integrated floating droplet electricity generator that uses natural water as both the electrode and the substrate. The device matches the performance of conventional generators while significantly reducing weight and cost, opening pathways to scalable, land-free clean energy applications.
- Journal
- National Science Review
Molecular “double bridges” perovskite solar cells to record performance
Science China PressPeer-Reviewed Publication
Researchers from Southern University of Science and Technology (SUSTech) and collaborators have built “double molecular bridges” across perovskite interfaces, unlocking ultrafast charge transport and pushing inverted perovskite solar cells to a certified fill factor of 88%, a new world record. The study was published in National Science Review (NSR).
- Journal
- National Science Review
Targeting immune checkpoint therapy: the role of manganese in tumor immunotherapy
Chinese Medical Journals Publishing House Co., Ltd.Peer-Reviewed Publication
•Mn2+ modulates the cyclic GMP-AMP synthase (cGAS) - stimulator of interferon gene (STING) pathway and promotes immunogenic cell death to enhance immune checkpoint therapy efficacy.
•Mn2+ binds to and activates cGAS, increasing its sensitivity to double-stranded DNA and promoting cyclic GMP-AMP (cGAMP) production.
•Manganese salts (e.g., MnJ) act as potent immune adjuvants that enhance both humoral and cellular immune responses.
- Journal
- Cancer Pathogenesis and Therapy
Breast cancer brain metastasis: bridging biological mechanisms to therapeutic innovations
Sichuan International Medical Exchange and Promotion AssociationPeer-Reviewed Publication
In a comprehensive review published in MedComm - Oncology, a research team sheds new light on the complex biology and therapeutic challenges of breast cancer brain metastasis (BCBrM). The authors detail the multi-step metastatic cascade, from primary tumor invasion to brain colonization, and highlight key signaling pathways such as TGF-β, Wnt/β-catenin, PI3K/AKT, Notch, HER2-HER3, and JAK/STAT. They also explore the dynamic interactions between tumor cells and the brain microenvironment, including astrocytes, microglia, and neurons, which facilitate immune evasion and metabolic adaptation. The review further discusses advances in preclinical models, emerging CNS-penetrant therapies, and innovative clinical trial designs, offering a roadmap for personalized management of BCBrM.
- Journal
- MedComm – Oncology