Copper imbalance linked to white matter development and social behavior in autism
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Oct-2026 19:17 ET (22-Oct-2026 23:17 GMT/UTC)
Researchers in Japan found that lower plasma copper levels and reduced white matter volume in individuals with autism spectrum disorder were associated with clinical symptom scores, including social symptom severity. Using a mouse model, they show that developmental copper deficiency disrupts brain vascular and metabolic signaling, impairs oligodendrocyte maturation and myelination, and alters social behavior through mitophagy and mTOR suppression.
Researchers at Tohoku University look beyond the life-taking venomous stings of box jellyfish, and focus on life-creating processes in a new comprehensive study of their reproductive traits.
Researchers have developed a new way to generate realistic synthetic training data for agricultural robots by recreating tomato cultivation environments in a virtual world. The approach could help overcome one of the biggest barriers in agricultural robotics: the time and labor required to collect and manually label real-world data under challenging greenhouse conditions such as changing lighting, dense foliage, and fruit occlusion.
What does it mean to weigh a $170 billion gold mine against a way of life? Researchers at Kyushu University and Oita University found that for Alaska Native communities, the answer cannot be reduced to simple ‘support’ or ‘opposition.’ Many community members occupy multiple, often conflicting roles, and must balance economic opportunity, cultural survival, and environmental stewardship. The findings call for governance structures that center Indigenous worldviews and their own definitions of well-being.
A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. The proposed drug is anticipated to bind strongly to the drug-metabolizing enzyme cytochrome P450 (CYP), thereby inhibiting excessive CYP-mediated metabolism and preventing the degradation of co-administered drugs. Additionally, because this agent targets enzymes released by the tuberculosis bacterium rather than the bacterium itself, the likelihood of bacterial mutation and resistance development is reduced, suggesting sustained therapeutic efficacy over an extended period.
β-1,2-Glucans are glucose-based polymers found across a wide range of organisms that play important roles in bacterial infection and symbiosis. However, how bacteria import these sugars remains poorly understood. In a recent study, researchers from Japan identified and characterized Chy400_4166, a novel β-1,2-glucan-binding protein from the bacterium Chloroflexus aurantiacus. This protein exhibits a binding mechanism distinct from any previously described transporter of this kind, expanding our understanding of how bacteria recognize and take up β-1,2-glucans.