The lord of the ring mouse
Reports and Proceedings
Updates every hour. Last Updated: 1-Nov-2025 12:11 ET (1-Nov-2025 16:11 GMT/UTC)
Tokyo, Japan – Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex molecular machinery like enzymes move while they help catalyze reactions. Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method promises unprecedented access to the mechanisms by which biomolecules work, and how they relate to illnesses.
In a study now published in Nature Plants, Dr. Yihong Feng (Specially Appointed Assistant Professor) and Professor Takashi Ueda at the National Institute for Basic Biology in Japan, together with their collaborators, demonstrated in the model plant Arabidopsis thaliana the existence of a retrograde trafficking pathway that retrieves the membrane protein VAMP727 from the vacuolar membrane back to endosomes. The team further identified the molecular machinery responsible for this pathway.
The COVID-19 pandemic presented several challenges, leaving the specific impact of class closures on student performance unclear. To address this, researchers examined the effect of pre-pandemic class closures due to influenza outbreaks on students’ test scores in Japan. They found that class closures adversely affected the math scores of elementary school boys from low-income households, likely due to lost instructional time and unhealthy behaviors. Fortunately, high-quality teachers could help students recover from the learning loss.
A novel spectroscopic method developed at Institute of Science Tokyo, Japan, enables highly sensitive analysis of molecules at material interfaces, using a combination of conventional ATR-IR, precise gap-control and advanced data processing. The technique offers a low-cost alternative to conventional interfacial spectroscopy and has potential applications in material sciences, nanotechnology, and biological sciences.
A spinel-type sulfide semiconductor that can emit light from violet to orange at room temperature has been developed by researchers at Science Tokyo, overcoming the efficiency limitations of current LED and solar cell materials. The material, (Zn,Mg)Sc2S4, can be chemically tuned to switch between n-type and p-type conduction, leading to future pn homojunction devices. This versatile semiconductor offers a practical path toward the development of more efficient LEDs and solar cells.
Harnessing quantum states that avoid thermalization enables energy harvesters to surpass traditional thermodynamic limits such as Carnot efficiency, report researchers from Japan. The team developed a new approach using a non-thermal Tomonaga-Luttinger liquid to convert waste heat into electricity with higher efficiency than conventional approaches. These findings pave the way for more sustainable low-power electronics and quantum computing.