Unveiling the mechanism of maintenance of replication and transcription in mitochondria
Peer-Reviewed Publication
Updates every hour. Last Updated: 5-May-2025 12:09 ET (5-May-2025 16:09 GMT/UTC)
Mitochondrial deoxyribonucleic acid (mtDNA) plays a crucial role in energy production and abnormalities in mtDNA are linked to various diseases. However, its regulatory mechanism remains insufficiently understood. Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between mtDNA transcription and replication. These findings provide valuable insights into mtDNA regulatory mechanism, potentially paving the way for the development of novel therapeutic strategies for the treatment of diseases and aging.
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