A study published in the journal Neuroimage: Clinical found that patients with Major Depressive Disorder, who had recovered from symptoms, were able to strengthen some of their brain connections, thereby increasing their self-esteem. The research showed that connectivity between certain brain regions - previously found to be decreased when feeling guilt in people with a history of depression - could be strengthened in a single session of neurofeedback training through functional magnetic resonance imaging.

Blood sugar levels in obese mice were controlled more efficiently when the mice were challenged with a glucose overload and treated with 12-HEPE, a lipid produced in response to cold by brown adipose tissue.