Paxlovid does not significantly reduce COVID-19 hospitalization and mortality among vaccinated older adults. The study questions the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.

Systems engineering researchers have developed a new technique to improve the efficiency of food-delivery operations. The technique accounts for the location of food distribution sites and delivery locations to develop optimized delivery routes that make food delivery faster and more fuel efficient.

Researchers identify predictive markers of response to immunotherapy treatment in a study involving data from over 700 patients across six different cohorts, published in Nature Communications. The study has significant relevance, impacting the management of bladder cancer patients. Machine learning tools enabled the identification of key variables for the success of immunotherapy treatment. This innovative methodology has allowed researchers to pinpoint which tumor subtypes respond best to immunotherapy.