The International Society for Stem Cell Research (ISSCR) is proud to announce the release of Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, a comprehensive new resource designed to accelerate the translation of human pluripotent stem cell (PSC)-derived therapies into clinical trials and commercial use.

Developed by leading international experts in cell therapy, this groundbreaking document outlines the key principles and decision points required to develop safe, effective, and regulatory compliant PSC-derived products. Organized into seven sections, the guidance offers jurisdictionally neutral information on topics ranging from PSC line selection and raw material use to regulatory considerations, preclinical studies, and clinical trials.

There may be a way to protect brain energy to preserve cognition — and the secret could lie on your plate. Think fish and seafood, meat, non-starchy vegetables, berries, nuts, seeds, eggs and even high-fat dairy products.

University of Missouri researchers are now testing just how powerful these foods can be. They’ve found that a high fat, low carb diet — known as the ketogenic diet — may not only preserve brain health but also stop or slow the signs of cognitive decline for those at higher risk of developing Alzheimer’s disease.

Deep brain stimulation, a method where specific brain regions are activated using implanted electrodes, is a well-established approach for treating movement disorders such as Parkinson’s disease. Researchers led by Christian Kell from Frankfurt University Medicine as well as Nils Warneke and Katrin Neumann from Münster University Hospital have now successfully alleviated severe stuttering in a person with developmental stuttering using this method for the first time. The researchers are now preparing a study to test the therapy on additional individuals who experience severe stuttering.