Centenarians often live to 100+ due to a combination of protective genetic factors, which account for up to 50%, and healthy lifestyles, such as plant-forward diets, regular, natural movement and strong social connections. While these “agers” often possess unique immune system signatures, understanding the metabolic signs of healthy aging is not yet fully understood.

In a new study from Boston University Chobanian & Avedisian School of Medicine, researchers have discovered that centenarians have a distinct blood metabolite pattern that is not just an extension of normal aging. In particular, they show uniquely higher levels of certain primary and secondary bile acids and preserved levels of several steroids, patterns that diverge from the typical age trends seen in non-centenarians and that are linked to lower death risk.  

A new study introduces the first step-by-step methodological guide for conducting umbrella reviews in education, addressing a major gap in evidence synthesis. Combining theory with a real case study on digital diaries, the publication supports novice researchers and strengthens evidence-based decision-making in education by offering a clear, structured, and field-specific approach to advanced research synthesis. It highlights the relevance, originality, and value of umbrella reviews for producing comprehensive, policy-relevant insights, while identifying key research gaps and advancing methodological rigor in educational research.

Study finds that pressure from parents can raise different kinds of perceived cost, with some tied more closely to burnout and others to achievement.

First systematic review to track long-term trends across pre- and post-pandemic periods finds dramatic rise in screen use among children and adolescents.