It’s a debilitating disease that affects more than 500,000 Australians, but new research from the University of South Australia is offering fresh hope to people living with rheumatoid arthritis (RA).

The review highlights how disrupting the cell cycle, a process often hijacked by cancer cells for unchecked growth offers a promising strategy for cancer therapy. It focuses on drugs that precisely target key cell cycle regulators, several of which are already in clinical use. By showcasing the latest breakthroughs and outlining future research directions, the article provides a comprehensive look at how targeting cell cycle dysregulation is shaping the future of cancer care.

Researchers have unveiled the transformative potential of micropattern arrays—engineered microstructures—to probe and guide cellular biomechanics. These arrays not only help decipher how cells sense physical cues but also steer tissue regeneration and stem cell fate, paving the way for breakthroughs in tissue regeneration, organ-on-a-chip systems, and disease modeling.

A groundbreaking study of 7000-year-old exposed coral reef fossils reveals how human fishing has transformed Caribbean reef food webs: as sharks declined by 75% and fish preferred by humans became smaller, prey fish species flourished —doubling in numbers and growing larger. This unprecedented look into prehistoric reef communities shows how the loss of top predators cascaded through the entire food web, shifting the balance amongst coral reefs