Eye for trouble: Automated counting for chromosome issues under the microscope
Peer-Reviewed Publication
Updates every hour. Last Updated: 11-Jan-2026 02:11 ET (11-Jan-2026 07:11 GMT/UTC)
Tokyo, Japan – Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope. Conventional analysis requires trained personnel and time, with variability between different people. The team’s machine-learning-based algorithm boasts an accuracy of 84% and gives a more objective measurement. This could be a game changer for diagnosing disorders tied to abnormal numbers of SCEs, like Bloom syndrome.