Circulating tumor cells (CTCs), originating from primary neoplastic tissues, infiltrate blood vessels, migrate through the bloodstream, and establish secondary tumor foci. The detection of CTCs holds significant promise for early-stage identification, diagnostic precision, therapeutic monitoring, and prognostic evaluation. It offers a non-invasive approach and has broad clinical relevance in cancer management. This comprehensive review primarily focused on CTCs as biomarkers in the diagnostic, therapeutic, and prognostic surveillance of hepatocellular carcinoma, compared their correlation with key clinical parameters and the identification of gene characteristics. It also highlighted current methodologies in CTC detection. Despite approval by the U.S. Food and Drug Administration for select malignancies, the comprehensive integration of CTCs into routine clinical practice requires procedural standardization and a deeper understanding of the underlying molecular intricacies. The challenges in CTC detection, including limited quantity, technical impediments, and cellular heterogeneity, call for concerted and further investigational efforts to advance precision in cancer diagnostics and prognostication, thus realizing the objectives of precise and personalized medicine.

Insilico Medicine(“Insilico”), a global leading generative artificial intelligence (AI)-driven biotechnology company, announces that Alex Zhavoronkov PhD, founder and CEO of Insilico Medicine will be attending the Fortune Global Forum 2024, participating in the panel titled “Rewiring Business: Unlocking AI’s Full Economic Potential” at 12:05-1:20 pm ET, November 12.

Professor Yasmine Belkaid, immunologist and President of the Institut Pasteur, has joined the international attractiveness campaign “MAKE IT ICONIC. Choose France*”, which aims to promote France's boldness and spirit of innovation, by showcasing the country's research, expertise, know-how and economic strength.

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a Nature Immunology study that describes how shutting off T cell access to inhibitory metabolites could be a promising new approach to cancer immunotherapy.

This study introduces a fibrous amorphous indium gallium zinc oxide material (IGZO) integrated into sensory face masks, providing real-time respiratory monitoring via a wireless flexible circuit. Enhanced surface area promotes gas diffusion, enabling precise detection of respiratory states. This innovation in wearable health monitoring highlights a promising direction for continuous physiological assessment.