NRG Oncology (NRG), a National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group focused on improving outcomes for adults with cancer through multi-center clinical research, recently announced the creation of a new Theranostics Subcommittee, as well as two leadership role updates within the organization’s current committees.

About The Study: This systematic review and meta-analysis found inverse associations and a dose-response association between fluoride measurements in urine and drinking water and children’s IQ across the large multi-country epidemiological literature. There were limited data and uncertainty in the dose-response association between fluoride exposure and children’s IQ when fluoride exposure was estimated by drinking water alone at concentrations less than 1.5 mg/L. These findings may inform future comprehensive public health risk-benefit assessments of fluoride exposures.

About The Study: This cross-sectional study’s analysis underscores a public health crisis of substance use disorder. The prevalence of substance use disorder surged during the COVID-19 pandemic, yet the receipt of treatment declined initially as health care services were disrupted. Treatment rates began to recover in 2022, likely due to reopened treatment programs and increased telehealth use.

Puberty blockers and gender-affirming hormones are rarely prescribed to U.S. transgender and gender diverse (TGD) adolescents, according to a new study from researchers at Harvard T.H. Chan School of Public Health, Harvard Pilgrim Health Care Institute, and FOLX Health.

About The Study: This longitudinal cohort study suggests that early-life infection burden may continue throughout childhood and is associated with later antibiotic treatments independent of social and environmental risk factors. These findings are important for prognosis and follow-up of children experiencing a high burden of common infections in early life.

Key Takeaways:

A new study in JAMA Internal Medicine led by the Harvard Pilgrim Health Care Institute examined whether doxycycline post-exposure prophylaxis (doxyPEP) was associated with declines in bacterial sexually transmitted infections in routine care.

The study represents the largest cohort of doxyPEP recipients reported globally to date.

Findings showed doxyPEP was associated with a 79% reduction in chlamydia, 80% reduction in syphilis, and 12% reduction in gonorrhea.