Medicine & Health
Updates every hour. Last Updated: 2-Jul-2025 21:10 ET (3-Jul-2025 01:10 GMT/UTC)
Human cardiac organoid model reveals antibacterial triclocarban promotes myocardial hypertrophy by interfering with endothelial cell metabolism
Science China PressPeer-Reviewed Publication
Heart failure is the terminal stage of various cardiovascular diseases, usually characterized by pathological myocardial hypertrophy. So far, the pathogenesis of heart failure is not fully understood. The global burden of cardiovascular disease and epidemiological evidence indicate that in addition to traditional risk factors such as genetic inheritance and hypertension, exposure to exogenous environmental pollutants is a new risk factor. In recent years, the use of antimicrobials has increased, resulting in more exposure of these substances to humans, raising concerns about potential risks to human and environmental health. According to the findings of this study, the exposure to antibacterial agent TCC may be a new risk factor for metabolic cardiovascular diseases. This conclusion is supported by physiological indicator tests and a combined analysis of metabolomics and transcriptomics in cardiac organoids.
- Journal
- Science Bulletin
New study suggests RNA present on surfaces of leaves may shape microbial communities
Indiana UniversityPeer-Reviewed Publication
- Journal
- Proceedings of the National Academy of Sciences
- Funder
- U.S. National Science Foundation
Scientists unveil surprising human vs mouse differences in a major cancer immunotherapy target
University of California - San DiegoPeer-Reviewed Publication
Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is significantly weaker than the human version, providing new information on how cancer treatments are developed.
- Journal
- Science Immunology
- Funder
- NIH/National Institutes of Health, Human Frontier Science Program, Japan Science and Technology Agency, American Cancer Society, Hartwell Foundation, Kinship Foundation, Pew Charitable Trusts
Multilingualism improves crucial cognitive functions in autistic children
University of California - Los Angeles Health SciencesPeer-Reviewed Publication
- Journal
- Autism Research
Study finds 25% of youth experienced homelessness in Denver in 2021, significantly higher than known counts
University of Colorado Anschutz Medical CampusPeer-Reviewed Publication
- Journal
- PEDIATRICS
Trends in screening for social risk in physician practices
JAMA NetworkPeer-Reviewed Publication
- Journal
- JAMA Network Open