EurekAlert! News by Subject: Medicine & Health - News by Subject: Medicine & Health

Medicine & Health

Updates every hour. Last Updated: 29-Dec-2025 11:11 ET (29-Dec-2025 16:11 GMT/UTC)

10-Jul-2025

Key epigenetic switch discovered: Loss of LSD1 triggers ovarian reserve depletion and premature failure

Science China Press
Peer-Reviewed Publication

Chinese researchers identified histone demethylase LSD1 as a critical guardian of ovarian reserve. When deleted in mouse oocytes, LSD1 deficiency disrupted mitochondrial homeostasis and triggered ferroptosis, causing massive loss of dormant primordial follicles. This discovery explains how dormant follicles ("second wave") are maintained differently from active follicles ("first wave") and provides a foundation for treating premature ovarian insufficiency.

Journal: Science Bulletin

10-Jul-2025

Children’s social media activity highlights emotional stress of living with long-term health issues

University of Plymouth
Peer-Reviewed Publication

A study led by experts in data science at the University of Plymouth has shown that children with multiple long-term health issues undergo severe emotional stress at the same time as they are trying to cope with the physical challenges of their condition. The esearch used AI language models to analyse sentiments and emotions expressed by almost 400 paediatric patients and their caregivers on social media.

Journal: Journal of Affective Disorders

10-Jul-2025

Genetics helps untangle the causes behind a rare and complex vascular disorder

The University of Osaka
Peer-Reviewed Publication

Researchers from The University of Osaka have identified key genetic mutations linked to extracranial arteriovenous malformations (AVMs), a rare and potentially serious vascular disorder. They have revealed that these mutations activate the RAS/RAF/MEK signaling pathway and that the MAP4K4 gene may drive pathological angiogenesis. This may mean that existing cancer drugs that target the same pathway could be effective for AVM treatment, potentially paving the way for novel therapies.

Journal: Virchows Archiv
Funder: Japan Society for the Promotion of Science, Kurozumi Medical Foundation, Mother and Child Health Foundation, Osaka Medical Research Foundation for Intractable Diseases

10-Jul-2025

Chemicals from turmeric and rhubarb could help fight antibiotic-resistant bacteria lurking in wastewater

Frontiers
Peer-Reviewed Publication

Antibiotic resistance poses a significant health threat worldwide. One underappreciated source of resistant bacteria is our wastewater, as bacteria in sewage evolve to survive small doses of antibiotics excreted by patients. Without proper treatment, these resistant bacteria could get into our water resources and cause infections, or transfer genes for antibiotic resistance to other bacteria. Scientists experimenting with natural compounds as potential water treatments have discovered that extracts of turmeric and rhubarb, curcumin and emodin, inhibit the activity of some strains of these resistant bacteria. In the future, we might be able to use them to control this source of antibiotic resistance.

Journal: Frontiers in Microbiology
Funder: Utah State University, U.S. Geographical Survey, U.S. National Science Foundation

9-Jul-2025

Lactate-induced mitochondrial calcium uptake 3 aggravates myocardial ischemia–reperfusion injury by promoting neutrophil extracellular trap formation

Research
Peer-Reviewed Publication

In order to elucidate the mechanisms underlying NET activation and its impact on MIRI, Hongru Zhang/Senlei Xu of Nanjing University of Chinese Medicine (NJUCM), along with Yanfei Mo of Pukou Hospital of Chinese Medicine, confirm that the generation of NETs by neutrophils exacerbates microvascular endothelial cell injury, thereby worsening MIRI.

Journal: Research
Funder: Natural Science Foundation of Jiangsu Province, Jiangsu Vocational College of Medicine Campus Local Collaborative Innovation Research Project, 2024 Nanjing Health Technology Development Project, Scientific Research Project of Jiangsu Provincial Health Commission

9-Jul-2025

Attending events is the ticket to happiness

University of South Australia
Peer-Reviewed Publication

The cold winter snaps might make it hard to get out and about, but new research led by the University of South Australia has found that frequently attending in-person events can significantly boost wellbeing.

Journal: International Journal of Tourism Research

9-Jul-2025

AI language models show promise in predicting liver cancer treatment outcomes

Hefei Institutes of Physical Science, Chinese Academy of Sciences
Peer-Reviewed Publication

A research team led by Prof. Hai Li from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, has become the first to systematically explore how large language models (LLMs) can assist in predicting liver cancer treatment responses—offering a new path toward AI-powered precision medicine.

Journal: Journal of Medical Systems