The potential of ribosome biogenesis in liver disease management
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-Dec-2025 19:11 ET (20-Dec-2025 00:11 GMT/UTC)
This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression. As the center of protein synthesis, ribosomes influence liver regeneration, hepatitis C virus (HCV) infection, nonalcoholic fatty liver disease (NAFLD), liver fibrosis, cirrhosis, and hepatocellular carcinoma. The article explores how disruptions in this process contribute to disease and how targeted therapies could offer new treatment avenues.
This article explores a new therapeutic approach for rheumatoid arthritis (RA) using a combination of triptolide and medicarpin. Recent research published in Engineering reveals that targeting the m6A methylation pathway can significantly reduce bone destruction associated with RA. The study demonstrates that the combined use of triptolide and medicarpin effectively inhibits osteoclastogenesis and modulates inflammation, offering a potential strategy to improve treatment outcomes and minimize side effects in RA patients.
A dual-protective approach using botulinum toxin (Botox) alongside an anti-nausea patch significantly reduces salivary gland toxicity in patients with metastatic prostate cancer undergoing PSMA-targeted radiopharmaceutical therapy. The strategy led to a 30 percent decrease in PSMA uptake by the salivary glands without affecting the treatment’s cancer-fighting efficacy. This reduction may enhance treatment adherence and improve overall patient outcomes. The findings were presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.
Aging and extreme heat together weaken gut and immune function.
The combination heightens risk of illness from a deadly, waterborne bacterium.
Findings suggest probiotics may help restore immune health in older individuals.