This study investigates the structural and functional alterations in cerebellar outputs in an autism mouse model (Nlgn3^R451C). The researchers used large-scale circuit tracing to map the projections from cerebellar nuclei to the thalamus, midbrain, and brainstem, identifying specific changes in innervation patterns. They also demonstrated that chemogenetic inhibition of a specific neuronal population in the zona incerta (ZI) could rescue social deficits in these mice.