A pharmaceutical product called TT-10, which spurs proliferation of heart muscle cells, was thought to offer promise to treat heart attacks. In a mouse heart-attack model several years ago, intraperitoneal injection of TT-10 at first promoted proliferation of heart muscle cells and showed declines in the size of the dead area of heart muscle. However, these early improvements were followed by worsened cardiac function at later time points. Now researchers show that a different delivery method, nanoparticle-mediated, slow-release of TT-10, enhances the potency and durability of TT-10 treatment for repair of heart muscle in the mouse heart-attack model.
- JCI Insight
- NIH/National Heart, Lung and Blood Institute, NIH/National Heart, Lung and Blood Institute, NIH/National Heart, Lung and Blood Institute, NIH/National Heart, Lung and Blood Institute
A new study led by researchers at UCLA Health has found that women over the age of 50 who had breastfed their babies performed better on cognitive tests compared to women who had never breastfed. The findings, published in Evolution, Medicine and Public Health, suggest that breastfeeding may have a positive impact on postmenopausal women’s cognitive performance and could have long-term benefits for the mother’s brain.
- Evolution Medicine and Public Health
Interleukin-12 – a messenger molecule of immune cells – was long considered to trigger the development of psoriasis. Now, researchers at the University of Zurich have shown that interleukin-12 does not actually cause the skin disease but protects against it. This also explains why common psoriasis drugs that block the messenger show insufficient treatment efficacy.
- Science Immunology
Burt’s Bees, a pioneer in natural skin care, today announced its latest research findings on the benefits of nature-based ingredients, including bakuchiol, aloe and rice milk, to improve and restore skin health across various skin priorities, types and tones. The studies will be presented at the in-person and virtual Integrative Dermatology Symposium (IDS) from October 22 – October 24, 2021.
- Integrative Dermatology Symposium
In 2015 a small team of Virginia Cooperative Extension agents, farmers, and representatives from state and federal conservation agencies from Northern Piedmont and Northern Shenandoah Valley created the Graze 300 VA Initiative “to enable Virginia farmers to achieve 300 days of livestock grazing per year by facilitating better pasture management and environmental stewardship.” Since then, Graze 300 VA has grown to 30 Extension agents and specialists working together with farmers across Virginia.
The American Physical Society awards the Rahman Prize to Argonne senior scientist Giulia Galli.