Collagen, the protein that builds skin, bones, tendons and organs, exists inside cells as a liquid-like droplet rather than the long, rigid rod seen in textbooks over the last half century, according to a new study from the Centre for Genomic Regulation (CRG) in Barcelona.

Sjögren’s disease is a widespread chronic autoimmune disorder that attacks the body’s own glands, yet its underlying disease mechanisms remain poorly understood. In a recent study, researchers from Japan discovered a self-reinforcing loop between different immune cells that sustains autoimmune responses in patients with Sjögren’s disease. Their findings pave the way for safer and more effective therapies.

The first published live observations of the rare goblin shark (Mitsukurina owstoni) in its natural deep ocean habitat were reported in a new paper by a University of Hawai‘i at Mānoa-led team of oceanographers. In the past, goblin sharks were only filmed and reported alive after being hooked on a fishing line and hauled to the surface, where divers could observe them and where they soon died. The new study, published in Journal of Fish Biology, documents two live observations of one of the most elusive but iconic sharks on the planet—one at a seamount near Jarvis Island and another on the slope of the Tonga Trench. 

A previously unknown physical connection between mitochondria and the nucleus offers new insight into how cells coordinate metabolism, development and gene regulation across multiple tissues.