A research team has successfully combined adaptive laboratory evolution (ALE) with metabolic engineering to create a strain of Escherichia coli that produces succinic acid (SA) from glycerol at significantly higher yields.

A team of researchers has uncovered how subtle structural changes in terpene synthases can dramatically improve the biosynthesis of miltiradiene, a critical intermediate in the production of pharmacologically valuable compounds such as tanshinone IIA, triptolide, and carnosic acid.

A research team has developed an innovative platform for producing lactate-based biodegradable plastics by harnessing a phosphite dehydrogenase (PtxD)-driven NADH regeneration system in Escherichia coli.

About The Study: The 1-year success rate in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK) with successfully prepared tissue was very high regardless of donor diabetes status. These results, supported by the separately reported finding that endothelial cell loss and cornea morphometry after 1 year were not affected by donor diabetes status, provide strong support for having no restrictions on the use of tissue from donors with diabetes for DMEK.