Researchers from Fudan University have developed an innovative glycopeptide enrichment strategy, offering a rapid and efficient tool for comprehensively profiling of glycosylation types, including N-glycosylation, O-GlcNAcylation, and O-GalNAcylation. This efficient method minimizes sample input and simplifies workflows, providing a powerful tool for studying glycosylation’s roles in biology and disease.

Can we examine the teeth of living fish and other vertebrates in detail, repeatedly over time, without harming them? 

Previously, small animals often had to be euthanized to obtain precise information, but now scientists have found a new way to humanely study detailed dental characteristics of vertebrates. This customizable method can be used for both living animals and museum specimens and has been published in the Journal of Morphology. 

Researchers at the Okinawa Institute of Science and Technology (OIST) and their collaborators applied human dental impression techniques to study fish teeth in a species called Polypterus senegalus. This fish has been separated from other fish species for about 360 million years. Due to this long period of evolutionary isolation, Polypterus still has many primitive characteristics that provide important information on the early development of bony fish.  

Researchers at Korea University have achieved a significant breakthrough in regenerative medicine. They have demonstrated how fibroblast growth factor 4 and Ascorbic acid, known as vitamin C, can induce the trans-differentiation of fibroblasts into functional cardiomyocytes. This discovery activates key cellular pathways and offers hope for developing treatments for cardiovascular diseases, the leading cause of death worldwide.