Dan G. Duda, DMD, PhD, of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Immunology Research, “Combination CXCR4 and PD1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma.”

New research from Curtin University has revealed increasing cigarette prices over the past several years have seen more older Australians turn to cannabis use as an alternative.

Researchers from Curtin’s School of Accounting, Economics and Finance investigated the buying habits of nearly 100,000 Australians from 2001 to 2019 by analysing data from the Australian National Drug Strategy Household Survey.

The team found when cigarette prices increased cannabis use decreased in Australians under 40 years of age, with no change for people aged between 40 and 50.

However, it also showed cannabis use increased among people aged over 50 when cigarette prices rose.

A new analysis published in the journal Science reveals that overfishing has caused populations of chondrichthyan fishes – sharks, rays, and chimaeras – to decline by more than 50 per cent since 1970. To determine the consequences, a team of researchers developed an aquatic Red List Index (RLI) which shows that the risk of extinction for chondrichthyan has increased by 19 per cent. The study also highlights that the overfishing of the largest species in nearshore and pelagic habitats could eliminate up to 22 per cent of ecological functions.

Chondrichthyans are an ancient and ecologically diverse group of over 1,199 fishes that are increasingly threatened by human activities. Overexploitation by target fisheries and incidental capture (bycatch), compounded by habitat degradation, climate change and pollution, has resulted in over one-third of chondrichthyans facing extinction. Here, the RLI was used to track the status of these species over the past 50-years.