A Korea University research team has discovered that pitavastatin, a widely used lipid-lowering drug, can directly inhibit the Mcl-1 protein—an essential survival factor for therapy-resistant triple-negative breast cancer (TNBC). By blocking Mcl-1–dependent mitochondrial protection, pitavastatin eliminates cancer stem-like cells, suppresses metastasis, and restores paclitaxel sensitivity in preclinical models. This repurposed drug may offer a safer, faster-to-deploy therapeutic strategy for patients with aggressive or chemotherapy-refractory TNBC.

A call for both distinguished global experts and rising early - career stars to join a systematic, multi - dimensional platform for biodiversity research.

Farmers and outdoor workers in the Northeast are facing an escalating threat of tick-borne diseases, which could be devastating to their livelihoods, according to new research led by Mandy Roome, associate director of the Tick-borne Disease Center at Binghamton University, State University of New York.

Cold Spring Harbor Laboratory’s Cifani lab has developed a new mass spectrometry technique that pushes the performance of their instruments to deliver scans that are more sensitive than ever before. Their innovation may improve drug target discovery while helping scientists answer long-standing questions about human health and biology.

A groundbreaking new study from Bar-Ilan University shows that one of sleep’s core functions originated hundreds of millions of years ago in jellyfish and sea anemones, among the earliest creatures with nervous systems. By tracing this mechanism back to these ancient animals, the research demonstrates that protecting neurons from DNA damage and cellular stress is a basic, ancient function of sleep that began long before complex brains evolved.