Researchers home in on tumor vulnerabilities to improve odds of treating glioblastoma
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Apr-2025 16:08 ET (29-Apr-2025 20:08 GMT/UTC)
A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen for genetic vulnerabilities in patient-derived cancer stem cells that represent the variability found in tumours.
Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells. The artificial genes can build intracellular structures through a cascading sequence that builds self-assembling structures piece by piece. The discovery offers a path toward using a suite of simple building blocks that can be programmed to make complex biomolecular materials, such as nanoscale tubes from DNA tiles. The same components can also be programmed to break up the design for different materials.
Researchers determine the genome of all subspecies of the extinct aurochs and show the history of its development into domestic cattle / publication in ‘Nature’
Hebrew University and National Academy of Sciences of Tajikistan uncover multi-layered site in Tajikistan's Zeravshan Valley, offering new insights into human expansion