Genomic maps untangle the complex roots of disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Jun-2026 21:15 ET (4-Jun-2026 01:15 GMT/UTC)
Drone footage revealed constant violations of Mexico’s whale shark tourism rules, even when far fewer boats were on the water than regulations allow. The findings raise broader questions about whether popular wildlife encounters — from manta rays and sea turtles to whales and even elephants — are truly “ecotourism” and highlight the need for stronger monitoring and community-led stewardship.
Metabolic dysfunction-associated steatotic liver disease (MASLD), a spectrum of liver conditions ranging from simple steatosis to steatohepatitis (MASH), fibrosis, and cirrhosis, represents a global health epidemic with no approved pharmacotherapies.
The liver plays a central role in maintaining systemic energy homeostasis during fasting by mobilizing lipid reserves, a process often accompanied by transient hepatic steatosis. Dimethylarginine dimethylaminohydrolase 1 (DDAH1), a key enzyme metabolizing asymmetric dimethylarginine (ADMA), has been shown to protect against NAFLD under nutrient-overload conditions. However, its role in the physiological context of fasting remained elusive.
Why do some children develop a brain that is too small (microcephaly)? An international research team involving the German Primate Center – Leibniz Institute for Primate Research (DPZ), Hannover Medical School (MHH), and the Max Planck Institute of Molecular Cell Biology and Genetics has used human brain organoids to investigate how changes in important structural proteins in the cell lead to this severe developmental disorder (EMBO Reports).