Inhibiting a specific gene, MET, in combination with standard chemotherapy and immunotherapy, enhances treatment efficacy and limits tumor growth in small cell lung cancer (SCLC). The study, led by the Hospital del Mar Research Institute, analyzed the effect of MET inhibition in mouse models and studied gene expression in patient tumor samples. The results are published in Cell Reports Medicine. Researchers aim to pursue this line of research with a clinical trial involving patients.

A groundbreaking study by marine scientists has revealed that sea-level rise in the Indian Ocean began accelerating far earlier than previously thought, with corals providing an unbroken natural record of ocean change stretching back to the early 20th century. Published in Nature Communications, the study was led by Professor Paul Kench from the National University of Singapore. By analysing coral samples from the Maldives in the central Indian Ocean, the scientists reconstructed a century-long chronology of sea-level changes and climate shifts with remarkable precision. They were able to extend the sea-level record for the Indian Ocean back a further 60 years, all the way to the early 1900s, offering a much longer and clearer historical context for interpreting modern sea-level changes.

Researchers demonstrate that Synthetic Biological Intelligence (SBI) systems react faster, more effectively to stimuli than state-of-the-art RL (reinforcement learning) algorithms. To access these properties, Cortical Labs - which led the research - built the world’s first biological computer, the CL1. With the establishment of a new approach, Bioengineered Intelligence (BI), researchers will seek to establish that engineered biological systems can surpass natural physiological limits, unlocking capabilities beyond those previously demonstrated

To help manage agricultural practices with fewer or no pesticides, University of Michigan researchers say they need to understand how ecological systems work on agricultural lands.