The ability of CD8⁺ T cells, a type of immune cell, to rapidly proliferate inside tumors is key to the success of cancer immunotherapy. In a new study, scientists from Tokyo University of Science, Japan, have identified a set of ‘signature’ genes that can determine whether these immune cells will multiply or stall within the tumor. Their findings provide a powerful pan-immunotherapy biomarker for treatment monitoring and pave the way for next-generation immunodynamic therapies.

Researchers at the HUN-REN Biological Research Centre, Szeged, Hungary, have developed an artificial-intelligence-assisted technology capable of analyzing up to one hundred patient-derived cell samples simultaneously.

The new method, described in Nature Communications, could significantly accelerate drug development and advance the field of personalized medicine.

Researchers at the HUN-REN Biological Research Centre in Szeged, Hungary, have developed an artificial-intelligence-assisted technology capable of analyzing up to one hundred patient-derived cell samples simultaneously.

The new method, described in Nature Communications, could significantly accelerate drug development and advance the field of personalized medicine.

Scientists from Trinity College Dublin have unearthed a “universal thermal performance curve” (UTPC) that seemingly applies to all species and dictates their responses to temperature change. This UTPC essentially “shackles evolution” as no species seem to have broken free from the constraints it imposes on  how temperature affects performance.

All living things are affected by temperature, but the newly discovered UTPC unifies tens of thousands of seemingly different curves that explain how well “species work” at different temperatures. And not only does the UTPC seem to apply to all species, but also to all measures of their performance with regard to temperature variation – whether you are measuring lizards running on a treadmill, sharks swimming in the ocean, or recording cell division rates in bacteria.

The effects of physical activity don’t stop when the movement does.   n a new study published in the Proceedings of the National Academy of Sciences, Virginia Tech researchers in collaboration with researchers at the University of Aberdeen and Shenzhen University found that being active adds to the total energy you use every day without causing the body to conserve energy in other ways.