Nexmifb regulates spinal motor neuron development via Efna5b in zebrafish
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Jun-2026 13:15 ET (13-Jun-2026 17:15 GMT/UTC)
A zebrafish study shows that the gene nexmifb is essential for spinal motor neuron development. Its loss reduces motor neurons and axon growth without causing cell death, primarily by downregulating the axon guidance gene efna5b. Restoring efna5b partially rescues these defects, confirming nexmifb acts through efna5b.
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