Exosomal miR-122-3p identified as key driver of metabolic dysfunction-associated steatotic liver disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-May-2026 01:15 ET (31-May-2026 05:15 GMT/UTC)
A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers have succeeded in developing a so-called nanobody that penetrates directly into human cells and can repair the chloride channel most commonly affected in cystic fibrosis. The innovative therapeutic approach was developed in collaboration between teams from Charité – Universitätsmedizin Berlin and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP). The results have now been published in the journal Nature Chemical Biology*.
The Biophysics Collaborative Access Team (BioCAT)—led by Illinois Institute of Technology faculty Thomas Irving, Professor of Biology; Weikang Ma, Professor of Biology; and Jesse Hopkins, Professor of Physics—has received the first installment of $2.6 million of a renewal award from the National Institute of General Medical Sciences of the National Institutes of Health to continue operating the BioCAT beamline at Sector 18-ID at the Advanced Photon Source at Argonne National Laboratory for the next five years.
MIT chemists have found that changing the composition of the cell membrane can alter the function of EGFR, a cell receptor that promotes proliferation and is often overactive in cancer cells.
A new study reveals that some of the ocean’s most powerful predators are running hotter, and that they are likely paying an increasingly steep price for it. The significance of this headline finding is the “double jeopardy” in which it places these iconic animals, which have high fuel demands due to their lifestyle and physiology, as they now face a future of warming oceans and declining food resources.
The research, led by scientists at Trinity College Dublin in collaboration with the University of Pretoria’s (UP) Faculty of Veterinary Science, shows that warm-bodied fish such as tunas and some sharks, including the legendary Great White and Ireland’s iconic basking shark, burn nearly four times more energy than their cold-blooded counterparts. This means they are likely to face an increasing risk of overheating as oceans warm, which may result in a reduction of suitable habitat and an enforced relocation towards the poles.