BUFFALO, NY — June 4, 2025 — A new editorial was published in Aging (Aging-US) Volume 17, Issue 5, on May 29, 2025, titled “Rethinking healthcare through aging biology.”

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection. A study led by researchers at the University of Barcelona has identified the DNA regions that activate the regeneration of this organ. The study, published in the journal Cell Genomics, provides a genome-wide map of the interactions between these regulatory elements of liver regeneration and the key genes involved in this process. The results provide a better understanding of the fundamental mechanisms of regeneration and could have future implications for the development of regenerative medicine. 

The development of ferroptosis-based nanotherapeutics is generally limited by poor penetration depth into tumors and potential systemic toxicity. 

In a recent issue of International Journal of Extreme Manufacturing, Tu and coworkers from Southern Medical University addressed these challenges by proposing the design and fabrication of self-propelled ferroptosis nanoinducers, composed of only two endogenous proteins with natural bioactivity.

This work offers a strategy for constructing a biocompatible cancer treatment paradigm with enhanced diffusion to achieve deeper penetration into tumor tissues, centered around the concept of ferroptosis.

A new study published in Nature Ecology & Evolution has found a simple rule that seems to govern how life is organised on Earth. The researchers believe this rule helps explain why species are spread the way they are across the planet. The discovery will help to understand life on Earth – including how ecosystems respond to global environmental changes.