In this study, we revealed the pulmonary pathogen profiles of immunosuppressed ICU patients based on CD4⁺T-cell counts: the severe group showed a predominance of fungal/rare infections, whereas in the moderate group, bacterial infections were prevalent, often involving oral commensals. These findings underscore the potential of immune-status stratification to guide more precise empirical antimicrobial therapy. Future large-scale, multicenter studies are warranted to validate these associations and their impact on clinical outcomes.

Two previously unknown species of fungi, Neohelicomyces coffeae and Neohelicomyces puerensis, have been found living on dead coffee plant branches in China. These belong to a group called Neohelicomyces, known for their unique, coiled shapes that look like tiny springs or spirals under a microscope. While many fungi in this group have been found in the wild, this study is significant because it explores how these organisms exist within agricultural environments, specifically in coffee-growing regions.

Researchers at the Wuhan Institute of Virology have decoded a critical survival strategy of the deadly Nipah virus (NiV), identifying a key host protein hijacked by the pathogen and translating this discovery into a promising new treatment approach. The work, published in Protein & Cell, addresses the urgent need for therapies against this high-mortality virus, for which no specific drugs currently exist.

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

An international consortium of more than 80 researchers from over 30 institutions across nine countries is calling for a coordinated, worldwide effort to map gene expression across every cell type and developmental stage of wheat.

The research showed that chronic pain is controlled by an entirely separate system than acute pain

POSTECH develops a platform for precise cellular control using "non-genetic DNA" decoupled from genetic information.