Ultra-high-gain MoS2 phototransistor enables room-temperature detection of few-photon signals and attomolar-level immunosensing
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Dec-2025 13:11 ET (28-Dec-2025 18:11 GMT/UTC)
Researchers have developed a novel MoS2 phototransistor with ultra-high gain, capable of detecting extremely weak light signals and attomolar concentrations of disease biomarkers at room temperature. This innovation paves the way for ultra-sensitive, rapid, and reliable point-of-care diagnostics.
To address the Ohmic losses and limited integration of conventional topological metasurfaces, Chinese scientists developed a novel approach by harnessing on-chip all-dielectric metasurfaces to precisely extract optical guided waves, replacing the loss-inducing role of metals. This strategy enables the creation and control of topological exceptional points in an all-dielectric environment, overcoming traditional limitations while leveraging the low-loss and high-integration advantages of on-chip dielectric platforms.
Label-free detection of biological events at single-cell resolution in the brain can non-invasively capture brain status for medical diagnosis and basic neuroscience research. We have developed a new label-free, multiphoton photoacoustic microscope (LF-MP-PAM) with a near-infrared femtosecond laser to observe endogenous NAD(P)H in living cells. We demonstrated the detection of endogenous NAD(P)H photoacoustic signals in brain slices to 700 μm depth and in cerebral organoids to 1100 μm depth.
Researchers from UNamur and Stanford have developed a compact, energy-efficient photonic device that steers light using twisted crystal layers. This innovation enables precise beam control, potentially revolutionizing satellite tracking, VR headsets, lasers, and quantum computing. The breakthrough uses fast simulations and machine learning to optimize design, offering a powerful new tool in light manipulation.