27-Mar-2025
How calcium may have unlocked the origins of life’s molecular asymmetry
Institute of Science TokyoPeer-Reviewed Publication
A group of researchers including scientists of the Earth-Life Science Institute (ELSI) at Institute of Science Tokyo have uncovered a surprising role for calcium in shaping the building blocks of life. Their study reveals that calcium ions help determine the molecular "handedness" (chirality) of tartaric acid polymers—an essential feature of biological molecules like DNA and proteins. This discovery sheds light on how life's uniform molecular structures may have first emerged on early Earth. In a twist on traditional theories, the researchers suggest that simple polyesters, in addition to peptides or nucleic acids, could have adopted this crucial trait on early Earth, offering a fresh perspective on life’s chemical origins.
- Journal
- Proceedings of the National Academy of Sciences
- Funder
- NSFC, International Partnership Program of the Chinese Academy of Sciences, RIKEN SPDR Program, JSPS Grant-in-Aid for Early Career Scientists, JSPS Grants-in-Aid, JSPS Grants-in-Aid, Tokyo Institute of Technology Yoshinori Ohsumi Fund for Fundamental Research, Mizuho Foundation for the Promotion of Sciences, Temporary Assistant Program by the DE&I Section of Science Tokyo (formerly Tokyo Institute of Technology), ELSI Brain Exchange Program