Record-breaking ultra-deep nanohole waveguides via femtosecond laser
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Apr-2026 00:16 ET (28-Apr-2026 04:16 GMT/UTC)
High-performance nanophotonic devices require extreme depth-to-diameter ratios, which are notoriously difficult to fabricate. Towards this goal, scientists in China developed a novel technique combining femtosecond laser writing with spherical-aberration enhancement to create nanohole-clad waveguides in single crystals. This breakthrough achieves record aspect ratios exceeding 50,000:1, enabling highly sensitive optical sensing and opening new avenues for 3D functional photonic integration and multi-functional integrated devices.
Traditional histopathological tissue analysis depends on staining, which translates biological structures into colors. By instead studying how the polarization state of light is altered, it is possible to extract information about the tissue without staining, while additionally gathering data suitable for automated analysis. In the published paper we present a metasurface polarimeter designed for such measurements and benchmark it against a commercially available system.
Researchers uncover a mechanism that may explain why biology consistently selects one molecular form over its mirror image. A new study suggests that life’s long-standing preference for one “handed” version of molecules, known as homochirality, may stem from a subtle quantum effect: electron spin. Researchers found that when electrons move through mirror-image molecules, their spin interacts differently with each form, causing small but meaningful differences in behavior during dynamic processes like chemical reactions or electron transport. Although these molecules are chemically identical in static conditions, this spin-driven asymmetry could make one version consistently more efficient over time, gradually leading to the dominance of a single “hand” in biology. The findings point to a surprising role for quantum physics in shaping the fundamental structure of life.
Wild gray bats adjust their echolocation calls based on the other bats in their flying group and the obstacles in their way, per analysis of a colony in Virginia.
Researchers at University of Toronto’s Department of Chemical Engineering & Applied Chemistry have made a key discovery about how certain bacterial strains produce a set of economically valuable chemicals — opening the door to new, more sustainable production methods. The finding, published in Nature Microbiology, shows how a family of molecules used in everything from cleaning products to cosmetics to nutritional supplements could be made via bacterial fermentation instead of from palm oil, as they are today.
New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our understanding of how bacteria manage DNA. The methods enabled researchers to uncover how the sequence, physical shape and flexibility of DNA guide the activity of an enzyme called DNA gyrase, which used to get all the credit for managing DNA. Their work uncovers that certain attributes of DNA are major players in this game. The study, which appeared in Nature Communications, has implications for antibiotic design.