Basophils, a type of white blood cell, promote recovery from acute respiratory distress syndrome (ARDS) in mice, according to researchers at Science Tokyo. In a mouse model of ARDS, basophils were found to release interleukin-4 (IL-4), which suppresses inflammatory neutrophils in the lungs during the recovery stage. The study suggests that targeting the basophil–IL-4–neutrophil pathway could offer a new therapeutic approach for ARDS, a condition with high mortality rates and no dedicated treatments.

Polyamines are natural molecules that promote healthy aging but are also linked to cancer progression, presenting a long-standing puzzle in biomedical research. In a recent study, researchers from Japan explored how polyamines affect cancer cells, uncovering a key interaction with protein eIF5A2. Their findings reveal that polyamines drive cancer growth by altering ribosomal gene expression, offering a potential target for selective cancer therapies and shedding light on the risks of polyamines.

Implantable microelectrodes that can safely capture brain activity are critical in neuroscience technologies. In a recent study, researchers from South Korea have developed a new class of polymer-carbon nanotube (CNT) based hybrid microelectrode arrays, which combine high electrical conductivity with mechanical softness. These advanced electrodes enable stable recording of brain signals while limiting inflammation and damage to brain tissue—paving the way for safer and smarter brain-computer interfaces.

New research from Michigan State University reveals that photorespiration – long considered a wasteful process – is essential for producing a crucial nutrient for preventing birth defects.

For the first time, scientists have measured how much carbon flows through photorespiration to make folates, a class of compounds that includes vitamin B9 – known for its importance as a prenatal vitamin. According to the study, led by MSU researcher Berkley Walker, about 6 percent of the carbon absorbed by plants is used to make folates. That number plummets by fivefold when photorespiration is suppressed.  

These findings, published in Nature Plants, could help scientists engineer plants to boost production of the nutrient important for human health. They also shed light on how a high-carbon dioxide world caused by climate change could make plants less nutritious.

A team of scientists at Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) has created a protein-based therapeutic tool  that could change the way we treat diseases caused by harmful or unnecessary cells. The new tool, published in Nature Biomedical Engineering, involves a synthetic protein called Crunch, short for Connector for Removal of Unwanted Cell Habitat. Crunch uses the body’s natural waste removal system to clear out specific target cells, offering hope for improved treatments for cancer, autoimmune diseases, and other diseases where harmful cells cause damage.