CRISPR’s efficiency triples with DNA-wrapped nanoparticles
Peer-Reviewed Publication
Updates every hour. Last Updated: 1-Sep-2025 16:11 ET (1-Sep-2025 20:11 GMT/UTC)
CRISPR gene-editing machinery could transform medicine but is difficult to get into tissues and disease-relevant cells. New delivery system loads CRISPR machinery inside spherical nucleic acid (SNA) nanoparticles. Particles entered cells three times more effectively, tripled gene-editing efficiency, and decreased toxicity compared to current delivery methods.
The natural phenomenon of upwelling, which occurs annually in the Gulf of Panama, failed for the first time on record in 2025. A study led by scientists from the Smithsonian Tropical Research Institute (STRI) indicates that the weakening of the trade winds was the cause of this event. This finding highlights the climate’s impact on fundamental oceanic processes and the coastal communities that depend on them