Plant-based diets can reduce the risk of multimorbidity
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Jan-2026 02:11 ET (13-Jan-2026 07:11 GMT/UTC)
Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue. That is why a team led by researchers from the University Hospital Bonn (UKB) and the University of Bonn investigated the influence of primary cilia dysfunction on adipocyte precursor cells in a mouse model. They found that overactivation of the Hedgehog signaling pathway causes abnormal development into connective tissue-like cells instead of white fat cells. Their findings have now been published in The EMBO Journal.
Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect ageing. The studies, which are published in Nature Aging, show that such mutations can reduce muscle strength and accelerate blood vessel ageing. The results can be of significance to the treatment of age-related diseases.
Based on the American Heart Association’s Life’s Essential 8 health metrics, cardiovascular health among older U.S. adults with certain cardiovascular diseases was suboptimal and declining.
An international, interdisciplinary research team led by Prof. Jakob N. Kather from the Else Kröner Fresenius Center (EKFZ) for Digital Health at TU Dresden analyzed seven independent patient cohorts from Europe and the USA using their newly developed AI model. The model detects genetic alterations and resulting tissue changes in colorectal cancer directly from tissue section images. This could enable faster and more cost-effective diagnostics in the future. For the development, validation, and data analysis of the model, experts in data and computer science, epidemiology, pathology, and oncology worked closely together. The study has been published in the journal “The Lancet Digital Health”.
Research shows that early childhood maltreatment is associated with significant delays in social and cognitive development. Unfortunately, according to the United States Department of Health and Human Services, children under age one face the highest risk of maltreatment, particularly neglect. The Child Protective Services (CPS) system is responsible for responding to maltreatment and preventing its recurrence. Most children with substantiated maltreatment reports remain with their parents, and CPS provides services to the parents (including substance use treatment or parenting classes) to rectify the conditions that led to maltreatment. Most foster care entries occur during early childhood, from the newborn period to five years old, but most research on foster care is focused on older children. Debate over the impacts of foster care has persisted for many years, yet little attention has been paid to the timing of children’s entry into foster care.
To remedy the gap in literature, researchers from the University of North Carolina at Greensboro and the Pennsylvania State University followed 8,795 Wisconsin children referred to CPS during their first year of life from birth until third grade. They examined the associations between the age of first foster care placement and school test scores, exposure to punitive discipline (suspension), and chronic absenteeism. The findings suggest that compared to no foster care intervention, foster care during early infancy is related to a higher likelihood of demonstrating basic or above reading skills and a lower likelihood of chronic absenteeism.
University of Warwick-led analysis of data from over 10,000 teenagers has found that sleep problems at age 14 are associated with self-harm behaviour at 14 and future self-harm at age 17.