The stem cell-based embryo model (SCBEM) takes advantage of the flexibility of pluripotent stem cells (non-reproductive cells that can give rise to many different types of cells) to resemble that of embryos. While this model has helped to advance research in diseases and develop therapies or treatments, it has also sparked international debate on what regulations should be placed on this type of experimentation. Researchers reviewed what countries are doing to regulate SCBEM and proposed what regulation should look like for this field of stem cell research to move forward in a manner that everyone can agree is ethically sound.