Supramolecular polymer science expands the scope of supramolecular chemistry and enriches the field of polymer science. It is expected to become an important contributor to scientific and technological progress for a sustainable society. A group of 37 international scholars from seven countries and regions, including China, Singapore, Germany, the UK, and the US, including Professor Xi Zhang from Tsinghua University, Professor Xiaodong Chen from Nanyang Technological University, Professor Frank Würthner from the University of Würzburg, Professor Oren A. Scherman from the University of Cambridge, Professor Amar Flood from Indiana University, Professor Feihe Huang from Zhejiang University, and Professor Junqi Sun from Jilin University, review the important progress in supramolecular polymer science in recent years from five perspectives: 1) driving forces of non-covalent polymerization, 2) polymerization methodologies, 3) physical mechanisms, 4) material morphology, and 5) engineering applications. They also raise nine fundamental questions and major challenges that urgently need to be addressed in response to future development needs: 1) synergy, 2) quantification, 3) spatiotemporal observation, 4) theoretical simulation, 5) digitalization, 6) recyclability, 7) healthcare, 8) energy conversion, and 9) large-scale manufacturing. They point out that the integration of new concepts, technologies, and methods, such as artificial intelligence, data-driven design, automated synthesis, and advanced manufacturing, supramolecular polymer science holds the keys to the development of recyclable materials, devices, and intelligent systems for sustainable social progress. This review is not only an in-depth summary and discussion, but also a collaborative initiative for the global multidisciplinary research community. The article was published as an open access Review in CCS Chemistry, the flagship journal of the Chinese Chemical Society.
