31-Oct-2025
First transplant in pigs of modified porcine kidneys with human renal organoids
Institute for Bioengineering of Catalonia (IBEC)Peer-Reviewed Publication
A research team has developed pioneering technology that enables human kidney organoids to be produced on a scalable basis. These organoids can then be combined with pig kidneys outside the body and transplanted back into the same animal in a viable manner.
The experiment, led by the Institute for Bioengineering of Catalonia (IBEC), is in the preclinical phase. It confirms the safety and viability of the procedure, paving the way for future trials involving humans.
In the long term, this approach could help to extend the useful life of organs intended for transplantation and provide an alternative therapy for patients with chronic kidney disease.
- Journal
- Nature Biomedical Engineering
- Funder
- European Research Council, Horizon 2020 research and innovation programme, Horizon 2020 research and innovation programme, Horizon 2020 research and innovation programme, Agencia Estatal de Investigación, Agencia Estatal de Investigación, Agencia Estatal de Investigación, Generalitat de Catalunya, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, Instituto de Salud Carlos III, “la Caixa” Foundation, Agencia Estatal de Investigación, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Cáncer, Gobierno de Navarra, Gobierno de Navarra, Instituto de Salud Carlos III, Generalitat de Catalunya, Marie Sklodowska-Curie Actions, Fundació la Marató de TV3