ASH 2025: AI uncovers how DNA architecture failures trigger blood cancer
Reports and Proceedings
Updates every hour. Last Updated: 7-Dec-2025 13:11 ET (7-Dec-2025 18:11 GMT/UTC)
EMBARGOED: A new study to be presented Dec. 6 at the 2025 American Society of Hematology (ASH) meeting reveals that even subtle disruptions in genome architecture can predispose individuals to lymphoma. This finding offers a new perspective on understanding and eventually treating blood cancers.
Since most people carry their phones with them every day, Shogo Takada is working on a way to use smartphone microphones to assist in locating disaster victims. The method combines two types of sound sources, monopole and dipole. In a disaster situation, a rescuer would emit two dipole sounds, which would be received by the microphone of a trapped victim, and then an electromagnetic wave would be sent from the victim’s phone to broadcast their location.
A major advancement in sustainable materials science: WPI researchers have engineered a new construction material that not only rivals concrete—it actually captures carbon during production. This breakthrough could change how we build homes, buildings, and infrastructure, offering a new pathway to low-carbon, resilient construction.
Scientists have made a nano breakthrough with a huge potential impact – one that puts printable electronics on the horizon. The scientists have solved a long-standing mystery governing the way layered materials behave, which has yielded a universal, predictive framework for the future of the 2D semiconductor industry.
Imagine wearable health sensors, smart packaging, flexible displays, or disposable IoT controllers all manufactured like printed newspapers. The same technology could underpin communication circuits, sensors, and signal-processing components made entirely from solution-processed 2D materials.
But until now, finding and developing the 2D materials that could enable such devices was largely trial and error.
Why does plastic turn brittle and paint fade when exposed to the sun for long periods? Scientists have long known that such organic photodegradation occurs due to the sun’s energy generating free radicals: molecules that have lost an electron to sunlight-induced ionization and have been left with an unpaired one, making them very eager to react with other molecules in the environment. However, the exact mechanisms for how and why the energy from the sun’s photons get stored and released in the materials over very long periods have eluded empirical evidence.
The problem lies in the timeframe. While scientists have access to extremely sophisticated spectroscopy equipment capable of measuring the energy levels of individual electrons at femtosecond to millisecond scales in organic materials, they have paid little attention to time scales beyond seconds – and these are processes that can take years.
As such, slow, transient charge accumulation has presented a disappointing data gap in both applied and theoretical optics. But now, researchers from the Organic Optoelectronics Unit at the Okinawa Institute of Science and Technology (OIST) have addressed this challenge with a new methodology that detects these faint signals. Their findings are published in Science Advances.