EurekAlert! News by Subject: Tech & Engineering

Tech & Engineering

Updates every hour. Last Updated: 29-Oct-2026 01:16 ET (29-Oct-2026 05:16 GMT/UTC)

1-Sep-2026

Integrated bioinformatic modeling of goniothalamin as a dual-target medicinal chemistry candidate against antibiotic-resistant Staphylococcus aureus and Escherichia coli

Bentham Science Publishers
Peer-Reviewed Publication

A new computational study has found that goniothalamin — a natural plant compound — binds tightly to two critical bacterial proteins in drug-resistant Staphylococcus aureus and Escherichia coli, suggesting it could form the basis of a new class of antibacterial agents that work differently from conventional antibiotics and may be less likely to drive resistance.

The study, "Integrated Bioinformatic Modeling of Goniothalamin as a Dual-target Medicinal Chemistry Candidate against Antibiotic-resistant Staphylococcus aureus and Escherichia coli," was co-authored by Nawan Nawan, Septi Handayani, and Agnes Immanuela Toemon, and published in The Open Medicinal Chemistry Journal.

Journal: The Open Medicinal Chemistry Journal

1-Sep-2026

How close are we to building a digital copy of the human brain?

University of Warwick
Peer-Reviewed Publication

Researchers from the University of Warwick report that how faithfully we can build a 'digital twin' of a human brain depends not only on computing power, but fundamentally on how much of the living brain we can measure, validate and update over time.

Journal: Nature Reviews Electrical Engineering

1-Sep-2026

New AI method helps robots learn from the past without being trapped by it

Science China Press
Peer-Reviewed Publication

Robots often learn from historical experience collected under older controllers and physical conditions. When tasks, hardware or environments change, that data can become misleading. Researchers developed Occupancy-Matching Policy Optimization (OMPO), which anchors large replay buffers to a small set of recent interactions. Across locomotion, transfer, manipulation and a real-robot test, OMPO improved stability, sample efficiency and adaptation.

Journal: National Science Review

1-Sep-2026

scLS: A computationally efficient differentially expressed gene detection algorithm

Waseda University
Peer-Reviewed Publication

Trajectory inference of single-cell RNA sequencing datasets enables tracking of cell dynamics over an inferred pseudotime. However, downstream analysis algorithms for the identification of differentially expressed genes and the handling of complex cell trajectories are lacking. Researchers have now developed scLS, which represents gene expression patterns in the frequency domain. It enables both dynamic and shifted expression tests and does not require explicit regression models or branch assignment, serving as an efficient first-pass screening tool.

Journal: Nucleic Acids Research

1-Sep-2026

Towards more reliable shaft resistance prediction for bored piles

Shibaura Institute of Technology
Peer-Reviewed Publication

Shaft resistance of large-diameter bored piles is commonly estimated using empirical adhesion (α) and friction (β) factors, but their values vary widely and remain poorly defined for intermediate geomaterials (IGMs). In a new study, researchers developed field-calibrated empirical correlations by back-analyzing 20 instrumented static load tests. The proposed equations improve prediction of shaft resistance in clay, sand, and IGMs, enabling more reliable and economical foundation design in soil–rock transition environments.