Recent progress on cobalt-based electrocatalysts for nitrate reduction to ammonia
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Oct-2026 06:16 ET (29-Oct-2026 10:16 GMT/UTC)
Ammonia is essential for fertilizers and is emerging as a zero‑carbon energy carrier, but its industrial production via the Haber‑Bosch process is energy‑intensive and emits large amounts of CO2. Meanwhile, nitrate pollution from agriculture and industry has contaminated groundwater worldwide, threatening ecosystems and human health. Electrocatalytic nitrate reduction to ammonia (NO3RR) offers an elegant solution: using renewable electricity to convert nitrate waste into valuable ammonia.
Mesenchymal stem cells (MSCs), due to their multilineage differentiation potential, represent a promising cell source for cartilage and bone regeneration, while bone morphogenetic protein 2 (BMP2) has been recognized as a potent inducer of chondrogenic and osteogenic differentiation. However, BMP2-driven cartilage formation is frequently accompanied by hypertrophic maturation and subsequent ossification, limiting its application in cartilage tissue engineering. Although parathyroid hormone-related protein (PTHrP), a critical regulator of skeletal development and endochondral ossification, has been implicated in maintaining chondrocyte proliferation and preventing premature hypertrophy, its precise role and the underlying mechanisms governing BMP2-induced osteochondral differentiation of MSCs remain poorly understood.
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