Chemotherapy-induced nausea and vomiting (CINV) represents one of the most distressing and debilitating side effects experienced by cancer patients undergoing treatment, significantly impacting quality of life, treatment adherence, and overall therapeutic outcomes. Neurokinin-1 receptor antagonists (NK1RAs) have emerged as cornerstone agents in the modern management of CINV, particularly for delayed-phase symptoms that occur 24-120 hours after chemotherapy administration. These agents target substance P binding to NK-1 receptors in both central and peripheral nervous system pathways, addressing the complex neurotransmitter mechanisms underlying CINV pathophysiology.

In the development of modern animal husbandry, the feed industry serves as a crucial material foundation, and extrusion puffing technology has become one of the mainstream feed processing technologies due to its unique advantages.

A new Doctoral Network coordinated by Tampere University has secured €4.4 million in funding from the European Union’s Marie Skłodowska-Curie Actions (MSCA) programme. The High-Power Optical Vortices (HiPOVor) project will train 15 doctoral researchers in the generation, amplification and application of high-power optical vortex beams. The consortium has set an ambitious goal: to establish optical vortex beams as a key enabling technology for advanced light-matter interaction.

With the continuous development of drug delivery technology, natural polyphenol self-assembled drug delivery systems (DDS) have become a research focus due to their unique advantages. Polyphenols can not only serve as drugs themselves but also as components of self-assembled drug delivery systems, broadening their application in the field of drug delivery. This article reviews the mechanisms of interactions between polyphenols and between polyphenols and other molecules, and analyzes the process of constructing drug delivery systems with polyphenols. At the same time, it deeply explores the multiple functions of polyphenol self-assembled complexes in drug delivery, such as enhancing drug efficacy, achieving precise targeted delivery, and overcoming biological barriers, highlighting their great potential in enhancing drug efficacy and reducing side effects. In addition, several advanced characterization and preparation techniques are introduced and discussed, which will help to deeply understand and evaluate the structure and performance of polyphenol self-assembled delivery systems, promoting their further development. Finally, the challenges and future intelligent manufacturing strategies of polyphenol self-assembled complexes are summarized.