Professor Ying-Wei Yang's research group at Jilin University successfully constructed an azobenzene-modified metal-organic framework (MOF)-based nano-impeller platform using a dimensional engineering strategy. They synthesized two-dimensional layered Zn-Azo-MOF-1 and three-dimensional network Zn-Azo-MOF-2 with the same composition but different dimensions. They found that the photoisomerization efficiency of the two-dimensional framework (cis isomer content 33%) was an order of magnitude higher than that of the three-dimensional framework (3%). Mechanical grinding triggered interlayer slip in the two-dimensional structure, breaking the spatial confinement and activating efficient photoisomerization. Analysis of rotational energy barriers and framework-ligand interactions revealed the mechanism by which dimensionality and mechanical activation synergistically regulate the photo-switching dynamics. The constructed two-dimensional Zn-Azo-MOF-1 achieved 99% cargo release within 50 minutes under alternating UV-Vis irradiation, successfully extending the nano-impeller function from an amorphous platform to a crystalline platform, providing a dimensional engineering design principle for the programmable switching behavior of stimulus-responsive materials. The article was published as an open access Research Article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.

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