Extracellular vesicles serve as essential mediators of communication between immune cells and tumor cells, and the recent advances in artificial induction strategies offer an adaptable and efficient platform for engineering extracellular vesicles, enabling their application as next-generation strategies in cancer immunotherapy.

The lithium-ion battery is a new energy storage device widely employed in various fields such as mobile power, electric vehicles, unmanned aerial vehicles, and spacecrafts due to its high energy, high efficiency, lightweight, and environmental friendliness. Understanding the internal mechanism of the battery is of utmost importance. The electrochemical model provides detailed insights into the internal mechanism of lithium batteries and encompasses the single-particle model and the P2D model, as well as enhancements such as thermal coupling, mechanical stress coupling, and electric double-layer capacitive coupling. However, the dispersion effect of capacitors in solid electrolyte interface (SEI) film capacitors and porous electrodes has been basically ignored, which is essential for analyzing the internal mechanism and managing energy conversion in lithium batteries experiencing short-term effects. Furthermore, the determination of the dominant order of the Faraday process and non-Faraday process within a short time period is essential for accurately predicting the lifespan of lithium batteries subjected to high-frequency periodic excitation and assessing performance degradation. While the frequency range of these two processes can be roughly delineated through electrochemical impedance spectroscopy (EIS), the precise transition time of their dominant positions remains uncertain.

In an Annenberg Public Policy Center white paper, biostatistician Jeffrey Morris of the University of Pennsylvania's Perelman School of Medicine analyzes the U.S. vaccine safety monitoring system and suggests how its components, including VAERS, can be improved.

Researchers at the University of Pennsylvania and University of Michigan have created the world’s smallest fully programmable, autonomous robots: microscopic swimming machines that can independently sense and respond to their surroundings, operate for months and cost just a penny each. Barely visible to the naked eye, the robots are smaller than grains of salt and could advance medicine, manufacturing and more.

Monoterpenoids are important plant-derived compounds widely used in fragrances, nutraceuticals, and medicinal applications. 

To address the global environmental and climate crisis and advance the UN SDGs, it is essential to fully leverage Earth observations (EO) through the integration of atmospheric, hydrological, cryospheric, lithospheric, ecological, and socio-economic data. Based on discussions from the 2023 “Towards Global Earth Observatory” workshop, this paper highlights the fragmented nature of current EO and data repositories and emphasizes the need for a more coordinated global Ground-Based Earth Observatory (GGBEO). We summarize the status of key in-situ and ground-based remote sensing systems and outline the actions required to build an integrated GGBEO with interoperable data repositories, unified observation networks, and sustainable long-term support.